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Lab Testing FAQ

Common questions about at-home blood tests and direct-to-consumer lab services.

Are at-home lab tests as accurate as tests ordered by my doctor?

Yes—if they use professional labs like Quest or LabCorp.

Services like Marek Health, Function Health, and InsideTracker send you to the same Quest/LabCorp facilities your doctor would use. The samples are processed identically. Accuracy is the same.

Finger-prick at-home kits (Everlywell, LetsGetChecked) are slightly less accurate (±3-5% variance) but fine for routine screening and trending over time.

Do I need to fast before lab tests?

Depends on what you're testing:

  • Fasting required (8-12 hours): Lipid panel, fasting glucose, insulin, comprehensive metabolic panels
  • No fasting needed: Hormones (testosterone, estrogen), thyroid (TSH), vitamin D, CBC
  • Morning best: Testosterone and cortisol (they fluctuate throughout the day)

Always check the specific requirements for your panel. Most services send detailed instructions.

What labs should I get as a baseline?

Start with these core markers (~$150-250 total):

  • Complete Blood Count (CBC): Red/white blood cells, overall health
  • Comprehensive Metabolic Panel (CMP): Kidney, liver function, electrolytes
  • Lipid Panel: Cholesterol (total, LDL, HDL), triglycerides
  • HbA1c: 3-month average blood sugar
  • TSH: Thyroid function
  • Vitamin D: Most people are deficient

This gives you a solid baseline. Add hormones (testosterone, estrogen) if optimizing performance or addressing symptoms.

Can I get lab tests without insurance?

Yes! That's the entire point of these services.

You don't need insurance, a doctor's referral, or pre-authorization. Just order, get tested, and receive results. Most services don't involve insurance at all—you pay cash/card directly.

However: You CAN use HSA/FSA funds for lab testing, since it's a qualified medical expense.

How often should I get labs done?

Depends on your situation:

  • Healthy baseline: Once per year
  • Optimizing/making changes: Every 3-6 months to track progress
  • On medications (TRT, thyroid, etc.): Every 3-6 months or as prescribed
  • Monitoring chronic conditions: Every 3 months or as recommended

Testing too frequently is wasteful—most markers don't change meaningfully week-to-week or even month-to-month.

What do I do if my results show something abnormal?

It depends on how abnormal:

Slightly out of range:

  • Don't panic—single values can fluctuate
  • Retest in a few weeks to confirm
  • Consider context (diet, sleep, stress before the test)
  • Services like Marek include physician consultation to interpret

Significantly abnormal or concerning values:

  • See a doctor ASAP
  • Bring your lab results with you
  • Don't try to self-treat serious abnormalities

At-home testing is great for optimization and tracking, but not a replacement for medical diagnosis when something might be seriously wrong.